Healthwise

Our Health Library information does not replace the advice of a doctor. Please be advised that this information is made available to assist our patients to learn more about their health. Our providers may not see and/or treat all topics found herein.

Integrated test during pregnancy (birth defects testing)

The integrated test is a screening test done during pregnancy to find out the chance that a baby has certain birth defects, such as Down syndrome. The test is done in two stages at two different times during the pregnancy. You will get the results after the tests in the second trimester are done.

  • The first stage can be done around 10 to 13 weeks of pregnancy. The tests done for this stage are:
    • An ultrasound. The ultrasound can show the age of the baby and measure the thickness of the skin at the back of the baby's neck (nuchal translucency, or NT).
    • A blood test to measure the level of a substance in the blood called pregnancy-associated plasma protein A (PAPP-A).
  • The second stage can usually be done between weeks 15 and 22. The tests done for this stage are all blood tests and include:
    • Alpha-fetoprotein (AFP).
    • Beta-human chorionic gonadotropin (hCG).
    • Unconjugated estriol (a form of estrogen).
    • Inhibin A.

The results of all these tests are reviewed to see if levels are higher or lower than expected, and the results are reported after the second stage.

Due to the threat of the COVID-19 (Coronavirus), we are taking precautionary measures to protect our staff and patients. We are implementing a temporary NO VISITOR policy at this time. Only patients or patients and their guardians will be allowed into the office. Please note, this is not to inconvenience anyone! The virus is a very real threat and it is essential that we stay healthy in order to provide needed care for our patients. If you are sick, we ask that you CALL the office to speak with a nurse before you come in. The nurse will provide specific instructions for you. Please DO NOT enter the office if you are sick (upper respiratory symptoms, fever, cough, or flu like symptoms). We are closely monitoring the situation and will update you as circumstances change. Thank you for your understanding!!